Cure for Obesity in a Pill?

Back in 2009, U of Michigan researcher Dr. Alan Saltiel published a study indicating that the genes IKKE and TBK1 have a major impact on metabolic balance and obesity. His research indicated that when someone cuts calories in an attempt to lose weight, IKKE and TBK1 become active and “act together as a sort of brake on metabolism.” You want to lose weight You go on a diet You cut calories IKKE and TBK1 become active Your metabolism slows down Weight loss stops You get frustrated… Eat a box of Krispy Kremes And gain back all that body fat Based on his thesis, Dr. Saltiel went searching for compounds that… would inhibit the expression of IKKE and TBK1 prevent reduced-calorie metabolism slowdown help calorie-counting dieters lose weight Using high-throughput chemical screening, the researchers came upon an approved off-patent drug – Amlexanox. Currently, amlexanox is being used to treat canker sores in the US and asthma in Japan for the past 25 years. More